by ROHIT
Bacterial Genomes and Infectious Diseases
Bacterial Genomes and Infectious Diseases
by V. L. (Ricky) Chan (Editor), Philip M. Sherman (Editor), Billy Bourke (Editor)
Product Details:
* Hardcover: 288 pages
* Publisher: Humana Press; 1 edition (July 8, 2006)
* Language: English
* ISBN-10: 158829496X
Book Description
The emergence and reemergence of infectious diseases, an increasing rate of antibiotic-resistant variants of pathogens, and the threat of bioterrorism underscore the importance of bacterial genomes and infectious diseases. Bacterial Genomes and Infectious Diseases presents major findings about bacterial genomes and their impact on strategy and approach for investigating mechanisms of pathogenesis of infectious diseases. This book imparts fundamental knowledge on the structure, organization, and evolution of bacterial genomes. The value and power of comparative genomics and proteomics, bioinformatics, microarrays, and knockout animal models in analyzing genomes, bacteria-host interactions and disease are demonstrated. Also discussed are the genomes of virulent and nonvirulent strains and species, origin and evolution of pathogens, different models of bacteria-host interactions, and diseases mechanisms.
Download
by V. L. (Ricky) Chan (Editor), Philip M. Sherman (Editor), Billy Bourke (Editor)
Product Details:
* Hardcover: 288 pages
* Publisher: Humana Press; 1 edition (July 8, 2006)
* Language: English
* ISBN-10: 158829496X
Book Description
The emergence and reemergence of infectious diseases, an increasing rate of antibiotic-resistant variants of pathogens, and the threat of bioterrorism underscore the importance of bacterial genomes and infectious diseases. Bacterial Genomes and Infectious Diseases presents major findings about bacterial genomes and their impact on strategy and approach for investigating mechanisms of pathogenesis of infectious diseases. This book imparts fundamental knowledge on the structure, organization, and evolution of bacterial genomes. The value and power of comparative genomics and proteomics, bioinformatics, microarrays, and knockout animal models in analyzing genomes, bacteria-host interactions and disease are demonstrated. Also discussed are the genomes of virulent and nonvirulent strains and species, origin and evolution of pathogens, different models of bacteria-host interactions, and diseases mechanisms.
Download
Gene Delivery to Mammalian Cells: Volume 2: Viral Gene Transfer Techniques
Gene Delivery to Mammalian Cells: Volume 2: Viral Gene Transfer Techniques (Methods in Molecular Biology)
by William C. Heiser (Editor)
Product Details:
* Hardcover: 592 pages
* Publisher: Humana Press; 1 edition (October 28, 2003)
* Language: English
* ISBN-10: 1588290956
Book Description
Highly experienced researchers describe in step-by-step detail methods that have proven most useful in delivering genes to mammalian cells. Volume 2: Viral Gene Transfer Techniques, details procedures for delivering genes to cells in vitro and in vivo, including the use of lentiviral vectors. An accompanying volume, Volume 1: Nonviral Gene Transfer Techniques focuses on gene delivery by a variety of chemical and physical methods, including ultrasound, biolistics, peptides, PNA clamps, liposomes, microinjection, electroporation, particle bombardment, dendrimers, and hydrodynamics.
Download
by William C. Heiser (Editor)
Product Details:
* Hardcover: 592 pages
* Publisher: Humana Press; 1 edition (October 28, 2003)
* Language: English
* ISBN-10: 1588290956
Book Description
Highly experienced researchers describe in step-by-step detail methods that have proven most useful in delivering genes to mammalian cells. Volume 2: Viral Gene Transfer Techniques, details procedures for delivering genes to cells in vitro and in vivo, including the use of lentiviral vectors. An accompanying volume, Volume 1: Nonviral Gene Transfer Techniques focuses on gene delivery by a variety of chemical and physical methods, including ultrasound, biolistics, peptides, PNA clamps, liposomes, microinjection, electroporation, particle bombardment, dendrimers, and hydrodynamics.
Download
Genomics, Proteomics, and Clinical Bacteriology: Methods and Reviews
Genomics, Proteomics, and Clinical Bacteriology: Methods and Reviews (Methods in Molecular Biology)
by Neil Woodford (Editor), Alan P. Johnson (Editor)
Product Details:
* Hardcover: 408 pages
* Publisher: Humana Press; 1 edition (May 12, 2004)
* Language: English
* ISBN-10: 1588292185
Book Description
An accessible introduction to how genomics has and will provide novel methods for bacterial investigation and advance our understanding and knowledge of bacterial pathogenicity. The authors critically evaluate the applications of genomics to diagnostic bacteriology, highlighting both current and likely future uses, describing real-time PCR methods, and outlining the promise of microarrays in clinical bacteriology. Their discussion examines in detail genomic approaches to antibacterial discovery, the nature of pathogenicity, the discovery of new pathogens, the exploration of the concept of clonality in bacteria, and bacterial taxonomics.
Download
by Neil Woodford (Editor), Alan P. Johnson (Editor)
Product Details:
* Hardcover: 408 pages
* Publisher: Humana Press; 1 edition (May 12, 2004)
* Language: English
* ISBN-10: 1588292185
Book Description
An accessible introduction to how genomics has and will provide novel methods for bacterial investigation and advance our understanding and knowledge of bacterial pathogenicity. The authors critically evaluate the applications of genomics to diagnostic bacteriology, highlighting both current and likely future uses, describing real-time PCR methods, and outlining the promise of microarrays in clinical bacteriology. Their discussion examines in detail genomic approaches to antibacterial discovery, the nature of pathogenicity, the discovery of new pathogens, the exploration of the concept of clonality in bacteria, and bacterial taxonomics.
Download
Genomics, Proteomics and Vaccines
Genomics, Proteomics and Vaccines
by Guido Grandi (Editor)
Product Details:
* Hardcover: 336 pages
* Publisher: Wiley (March 19, 2004)
* Language: English
* ISBN-10: 0470856165
Book Description
While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly.
Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens.
This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions.
Download
by Guido Grandi (Editor)
Product Details:
* Hardcover: 336 pages
* Publisher: Wiley (March 19, 2004)
* Language: English
* ISBN-10: 0470856165
Book Description
While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly.
Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens.
This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions.
Download
Enzyme Assays
Enzyme Assays: High-throughput Screening, Genetic Selection and Fingerprinting
by Jean-Louis Reymond (Editor)
Product Details:
* Hardcover: 386 pages
* Publisher: Wiley-VCH (March 10, 2006)
* Language: English
* ISBN-10: 3527310959
Book Description
Edited by one of the leading experts in the field, this book fills the need for a book presenting the most important methods for high-throughput screenings and functional characterization of enzymes. It adopts an interdisciplinary approach, making it indispensable for all those involved in this expanding field, and reflects the major advances made over the past few years.
For biochemists, analytical, organic and catalytic chemists, and biotechnologists.
Download
by Jean-Louis Reymond (Editor)
Product Details:
* Hardcover: 386 pages
* Publisher: Wiley-VCH (March 10, 2006)
* Language: English
* ISBN-10: 3527310959
Book Description
Edited by one of the leading experts in the field, this book fills the need for a book presenting the most important methods for high-throughput screenings and functional characterization of enzymes. It adopts an interdisciplinary approach, making it indispensable for all those involved in this expanding field, and reflects the major advances made over the past few years.
For biochemists, analytical, organic and catalytic chemists, and biotechnologists.
Download
Diagnostic Bacteriology Protocols
Diagnostic Bacteriology Protocols (Methods in Molecular Biology)
by Louise OConnor (Editor)
Product Details:
* Hardcover: 236 pages
* Publisher: Humana Press; 2 edition (April 21, 2006)
* Language: English
* ISBN-10: 158829594X
Book Description
This fully updated edition includes the novel identification, detection, and typing technologies that are transforming the field of diagnostic testing. The authors, working at the forefront of diagnostic test development, highlight these new technologies and describe current and future molecular diagnostic tests and related nucleic acid extraction methods. The protocols range from advanced molecular detection, quantification, and typing systems, to protocols for diagnostic protein identification, serological testing, and cell culture-based assays. The emphasis is on nucleic acid-based diagnostics and alternative biochemically- and immunologically-based formats that can provide significant potential for multiparameter testing and automation.
Download
by Louise OConnor (Editor)
Product Details:
* Hardcover: 236 pages
* Publisher: Humana Press; 2 edition (April 21, 2006)
* Language: English
* ISBN-10: 158829594X
Book Description
This fully updated edition includes the novel identification, detection, and typing technologies that are transforming the field of diagnostic testing. The authors, working at the forefront of diagnostic test development, highlight these new technologies and describe current and future molecular diagnostic tests and related nucleic acid extraction methods. The protocols range from advanced molecular detection, quantification, and typing systems, to protocols for diagnostic protein identification, serological testing, and cell culture-based assays. The emphasis is on nucleic acid-based diagnostics and alternative biochemically- and immunologically-based formats that can provide significant potential for multiparameter testing and automation.
Download
Transplantation Immunology: Methods and Protocols
Transplantation Immunology: Methods and Protocols (Methods in Molecular Biology)
by Philip Hornick (Editor)
Product Details:
* Hardcover: 440 pages
* Publisher: Humana Press; 1 edition (March 1, 2006)
* Language: English
* ISBN-10: 1588295443
Book Description
Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.
Download
Password:nguyenhuy
by Philip Hornick (Editor)
Product Details:
* Hardcover: 440 pages
* Publisher: Humana Press; 1 edition (March 1, 2006)
* Language: English
* ISBN-10: 1588295443
Book Description
Leading clinicians and scientists in solid organ transplantation review the current status of the field and describe cutting-edge techniques for detecting the immune response to the allografted organ. The authors present the latest techniques for HLA typing, detecting HLA antibodies, and monitoring T-cell response, and examine more specialized methods utilizing proteomics, laser dissection microscopy, and real-time polymerase chain reaction. The area of tolerance induction and reprogramming of the immune system is also covered, along with a discussion of up-to-date methods of organ preservation, of today's optimal immunosuppressive drug regimens, as well as the difficulty of mimicking chronic rejection in experimental models. Introductory chapters provide a theoretical update on current practices in renal, liver, islet, and lung transplantation and on the pathways of antigen presentation and chronic rejection.
Download
Password:nguyenhuy
Integrins
Integrins, Volume 426 (Methods in Enzymology)
by David A. Cheresh (Editor)
Product Details:
* Hardcover: 500 pages
* Publisher: Academic Press (August 27, 2007)
* Language: English
* ISBN-10: 0123739241
Book Description
An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells. It plays a role in the attachment of a cell to the extracellular matrix (ECM) and to other cells, and in signal transduction from the ECM to the cell. There are many types of integrin, and many cells have multiple types on their surface. Integrins are of vital importance to all metazoans, from humans to sponges. This volume in Methods in Enzymology presents methods for studying integrins.
Download
by David A. Cheresh (Editor)
Product Details:
* Hardcover: 500 pages
* Publisher: Academic Press (August 27, 2007)
* Language: English
* ISBN-10: 0123739241
Book Description
An integrin, or integrin receptor, is an integral membrane protein in the plasma membrane of cells. It plays a role in the attachment of a cell to the extracellular matrix (ECM) and to other cells, and in signal transduction from the ECM to the cell. There are many types of integrin, and many cells have multiple types on their surface. Integrins are of vital importance to all metazoans, from humans to sponges. This volume in Methods in Enzymology presents methods for studying integrins.
Download
RNA Editing
RNA Editing, Volume 424 (Methods in Enzymology)
by Jonatha Gott (Editor)
Product Details:
* Hardcover: 560 pages
* Publisher: Academic Press; 1 edition (August 6, 2007)
* Language: English
* ISBN-10: 0123739225
Book Description
RNA processing plays a critical role in realizing the full potential of a given genome. One means of achieving protein diversity is through RNA editing. A diverse array of editing events has been characterized, affecting gene expression in organisms from viruses and single cell parasites to humans and plants. The variety of editing mechanisms has required the development of many different experimental approaches, many of which are likely to be broadly applicable, particularly given the interplay between editing and other cellular processes, including transcription, splicing, and RNA silencing. This volume not only covers most of the principal methods employed in the field, but also offers innovative solutions to the significant challenges posed by these experimental systems.
Download
by Jonatha Gott (Editor)
Product Details:
* Hardcover: 560 pages
* Publisher: Academic Press; 1 edition (August 6, 2007)
* Language: English
* ISBN-10: 0123739225
Book Description
RNA processing plays a critical role in realizing the full potential of a given genome. One means of achieving protein diversity is through RNA editing. A diverse array of editing events has been characterized, affecting gene expression in organisms from viruses and single cell parasites to humans and plants. The variety of editing mechanisms has required the development of many different experimental approaches, many of which are likely to be broadly applicable, particularly given the interplay between editing and other cellular processes, including transcription, splicing, and RNA silencing. This volume not only covers most of the principal methods employed in the field, but also offers innovative solutions to the significant challenges posed by these experimental systems.
Download
RNA Interference, Editing, and Modification: Methods and Protocols
RNA Interference, Editing, and Modification: Methods and Protocols (Methods in Molecular Biology)
by Jonatha M. Gott (Editor)
Product Details:
* Hardcover: 456 pages
* Publisher: Humana Press; 1 edition (April 15, 2004)
* Language: English
* ISBN-10: 1588292428
Book Description
A comprehensive collection of cutting-edge methods for elucidating the function of new genes and altering gene expression. These readily reproducible techniques can be used either in transient and stable gene splicing applied to worms, flies, trypanosomes, mammals, and plants, or in studying RNA editing mechanisms in a wide range of organisms, including systems that involve the conversion of one base to another and insertion/deletion editing. Topics of interest include stable and transient RNA interference, gene silencing, RNA editing, bioinformatics, small noncoding RNAs, and RNomics. Special attention is given to methods for the identification and characterization of small RNAs involved in RNA interference or modification.
Download
by Jonatha M. Gott (Editor)
Product Details:
* Hardcover: 456 pages
* Publisher: Humana Press; 1 edition (April 15, 2004)
* Language: English
* ISBN-10: 1588292428
Book Description
A comprehensive collection of cutting-edge methods for elucidating the function of new genes and altering gene expression. These readily reproducible techniques can be used either in transient and stable gene splicing applied to worms, flies, trypanosomes, mammals, and plants, or in studying RNA editing mechanisms in a wide range of organisms, including systems that involve the conversion of one base to another and insertion/deletion editing. Topics of interest include stable and transient RNA interference, gene silencing, RNA editing, bioinformatics, small noncoding RNAs, and RNomics. Special attention is given to methods for the identification and characterization of small RNAs involved in RNA interference or modification.
Download
Food Microbiology Protocols
Food Microbiology Protocols (Methods in Biotechnology)
by John F. T. Spencer (Editor), Alicia L. Ragout de Spencer (Editor)
Product Details:
* Hardcover: 512 pages
* Publisher: Humana Press; 1st edition (December 12, 2000)
* Language: English
* ISBN-10: 089603867X
Book Description
Expert laboratorians present a wide ranging set of detailed techniques for investigating the nature, products, and extent of the microorganisms involved in the manufacture and spoilage of foodstuff. The methods cover pathogenic organisms that cause spoilage, microorganisms in fermented foods, and microorganisms producing metabolites that affect the flavor or nutritive value of foods. Included in the section dealing with fermented foods are procedures for the maintenance of lactic acid bacteria, the isolation of plasmid and genomic DNA from species Lactobacillus, and the determination of proteolytic activity of lactic acid bacteria. A substantial number of chapters are devoted to yeasts, their use in food and beverage production, and techniques for improving industrially important strains. Comprehensive and timely, Food Microbiology Protocols is a gold-standard collection of readily reproducible techniques essential for the study of the wide variety of microorganisms involved in food production, quality, storage, and preservation today.
Download
by John F. T. Spencer (Editor), Alicia L. Ragout de Spencer (Editor)
Product Details:
* Hardcover: 512 pages
* Publisher: Humana Press; 1st edition (December 12, 2000)
* Language: English
* ISBN-10: 089603867X
Book Description
Expert laboratorians present a wide ranging set of detailed techniques for investigating the nature, products, and extent of the microorganisms involved in the manufacture and spoilage of foodstuff. The methods cover pathogenic organisms that cause spoilage, microorganisms in fermented foods, and microorganisms producing metabolites that affect the flavor or nutritive value of foods. Included in the section dealing with fermented foods are procedures for the maintenance of lactic acid bacteria, the isolation of plasmid and genomic DNA from species Lactobacillus, and the determination of proteolytic activity of lactic acid bacteria. A substantial number of chapters are devoted to yeasts, their use in food and beverage production, and techniques for improving industrially important strains. Comprehensive and timely, Food Microbiology Protocols is a gold-standard collection of readily reproducible techniques essential for the study of the wide variety of microorganisms involved in food production, quality, storage, and preservation today.
Download
RNA Modification
RNA Modification, Volume 425 (Methods in Enzymology)
by Jonatha Gott (Editor)
Product Details:
* Hardcover: 480 pages
* Publisher: Academic Press; 1 edition (August 6, 2007)
* Language: English
* ISBN-10: 0123741556
Book Description
The presence of modified nucleotides in cellular RNAs has been known for decades and over 100 distinct RNA modifications have been characterized to date. While the exact role of many of these modifications is still unclear, many are highly conserved across evolution and most contribute to the overall fitness of the organism. In recent years, new methods and bioinformatics approaches have been developed for the dissection of modification pathways and functions. These methods intersect a number of related fields, ranging from RNA processing to comparative genomics and systems biology. In addition, many of the techniques described in this volume have broad applicability, particularly in regards to the isolation, characterization, and reconstitution of ribonucleoprotein complexes, expanding the experimental repertoire available to all RNA researchers.
Download
by Jonatha Gott (Editor)
Product Details:
* Hardcover: 480 pages
* Publisher: Academic Press; 1 edition (August 6, 2007)
* Language: English
* ISBN-10: 0123741556
Book Description
The presence of modified nucleotides in cellular RNAs has been known for decades and over 100 distinct RNA modifications have been characterized to date. While the exact role of many of these modifications is still unclear, many are highly conserved across evolution and most contribute to the overall fitness of the organism. In recent years, new methods and bioinformatics approaches have been developed for the dissection of modification pathways and functions. These methods intersect a number of related fields, ranging from RNA processing to comparative genomics and systems biology. In addition, many of the techniques described in this volume have broad applicability, particularly in regards to the isolation, characterization, and reconstitution of ribonucleoprotein complexes, expanding the experimental repertoire available to all RNA researchers.
Download
Regulatory RNAs
Regulatory RNAs
by Bruce Stillman (Editor), David Stewart (Editor)
Product Details:
* Paperback: 550 pages
* Publisher: Cold Spring Harbor Laboratory Press; 1 edition (June 30, 2007)
* Language: English
* ISBN-10: 0879698187
Download
by Bruce Stillman (Editor), David Stewart (Editor)
Product Details:
* Paperback: 550 pages
* Publisher: Cold Spring Harbor Laboratory Press; 1 edition (June 30, 2007)
* Language: English
* ISBN-10: 0879698187
Download
MicroRNA Methods
MicroRNA Methods, Volume 427 (Methods in Enzymology)
by John J. Rossi (Editor)
Product Details:
* Hardcover: 304 pages
* Publisher: Academic Press; 1 edition (September 4, 2007)
* Language: English
* ISBN-10: 0123739179
Book Description
MicroRNAs (miRNA) are tiny bits of genetic material that were unknown nearly 10 years ago but now represent an exciting field of study in biology. Upon their discovery, researchers revealed for the first time a new mechanism by which microRNA can stop the function of messenger RNA (mRNA) by literally cutting it in half, interfering with the normal function of specific messenger RNAs in gene expression.
This "expression" of genes that code for essential proteins is essentially what controls whether a cell turns into a liver, lung, or brain cell, for example. Understanding what activates this process or stops it is a key to understanding the biological process and builds a foundation for advances in medicine and other fields. This volume in Methods in Enzymology presents valuable methods for studying MicroRNA, with three sections covering identification of MicroRNAs and their targets; Micro RNA expression, maturation and functional analysis; and MicroRNAs and disease.
Download
by John J. Rossi (Editor)
Product Details:
* Hardcover: 304 pages
* Publisher: Academic Press; 1 edition (September 4, 2007)
* Language: English
* ISBN-10: 0123739179
Book Description
MicroRNAs (miRNA) are tiny bits of genetic material that were unknown nearly 10 years ago but now represent an exciting field of study in biology. Upon their discovery, researchers revealed for the first time a new mechanism by which microRNA can stop the function of messenger RNA (mRNA) by literally cutting it in half, interfering with the normal function of specific messenger RNAs in gene expression.
This "expression" of genes that code for essential proteins is essentially what controls whether a cell turns into a liver, lung, or brain cell, for example. Understanding what activates this process or stops it is a key to understanding the biological process and builds a foundation for advances in medicine and other fields. This volume in Methods in Enzymology presents valuable methods for studying MicroRNA, with three sections covering identification of MicroRNAs and their targets; Micro RNA expression, maturation and functional analysis; and MicroRNAs and disease.
Download
Vaccinia Virus and Poxvirology: Methods and Protocols
Vaccinia Virus and Poxvirology: Methods and Protocols
by Stuart N. Isaacs (Editor)
Product Details:
* Hardcover: 416 pages
* Publisher: Humana Press; 1 edition (April 19, 2004)
* Language: English
* ISBN-10: 1588292290
Book Description
A comprehensive collection of cutting-edge methods to study and work with the vaccinia virus and other poxvirus gene transcriptions. These readily reproducible techniques can be used for the construction and characterization of recombinant viruses; for the study of poxvirus gene transcription and DNA replication; for the investigation of the binding, entry, and movement of the virus in host cells; and for the use of the virus in immunologic and cell-cell fusion assays. Other methods cover poxvirus bioinformatics, aspects of viral pathogenesis at both a protein and an animal model level, and the study of immune responses to poxviruses-the latter a critical ability given the important role of vaccinia virus in smallpox vaccination and their potential role as vaccine vectors directed against infectious agents and cancer.
Download
by Stuart N. Isaacs (Editor)
Product Details:
* Hardcover: 416 pages
* Publisher: Humana Press; 1 edition (April 19, 2004)
* Language: English
* ISBN-10: 1588292290
Book Description
A comprehensive collection of cutting-edge methods to study and work with the vaccinia virus and other poxvirus gene transcriptions. These readily reproducible techniques can be used for the construction and characterization of recombinant viruses; for the study of poxvirus gene transcription and DNA replication; for the investigation of the binding, entry, and movement of the virus in host cells; and for the use of the virus in immunologic and cell-cell fusion assays. Other methods cover poxvirus bioinformatics, aspects of viral pathogenesis at both a protein and an animal model level, and the study of immune responses to poxviruses-the latter a critical ability given the important role of vaccinia virus in smallpox vaccination and their potential role as vaccine vectors directed against infectious agents and cancer.
Download
Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas
Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas : Molecular Genetics: Liver and Pancreatic Carcinomas
by M. A. Hayat (Editor)
Product Details:
* Hardcover: 480 pages
* Publisher: Academic Press (August 31, 2005)
* Language: English
* ISBN-10: 0120884046
Book Description
Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer.
This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today.
Download
by M. A. Hayat (Editor)
Product Details:
* Hardcover: 480 pages
* Publisher: Academic Press (August 31, 2005)
* Language: English
* ISBN-10: 0120884046
Book Description
Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer.
This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today.
Download
Yeast Gene Analysis
Yeast Gene Analysis, Volume 36, Second Edition (Methods in Microbiology)
by Ian Stansfield (Editor), Mike Stark (Editor)
Product Details:
* Paperback: 650 pages
* Publisher: Academic Press; 2 edition (May 29, 2007)
* Language: English
* ISBN-10: 0123694795
Book Description
Focusing on Saccharomyces cerevisiae, the second edition of Yeast Gene Analysis represents a major reworking of the original edition, with many completely new chapters and major revisions to all previous chapters. Originally published shortly after completion of the yeast genome sequence, the new edition covers many of the major genome-wide strategies that have been developed since then such as microarray analysis of transcription, synthetic gene array studies, protein microarrays and chemical genetic approaches. It represents a valuable resource for any research laboratory using budding yeast as their experimental system in which to identify new yeast gene functions. The chapters are written in a readable style with useful background information, technical tips and specific experimental protocols included as appropriate, enabling both the novice and the experienced yeast researcher to adopt new procedures with confidence.
Download
by Ian Stansfield (Editor), Mike Stark (Editor)
Product Details:
* Paperback: 650 pages
* Publisher: Academic Press; 2 edition (May 29, 2007)
* Language: English
* ISBN-10: 0123694795
Book Description
Focusing on Saccharomyces cerevisiae, the second edition of Yeast Gene Analysis represents a major reworking of the original edition, with many completely new chapters and major revisions to all previous chapters. Originally published shortly after completion of the yeast genome sequence, the new edition covers many of the major genome-wide strategies that have been developed since then such as microarray analysis of transcription, synthetic gene array studies, protein microarrays and chemical genetic approaches. It represents a valuable resource for any research laboratory using budding yeast as their experimental system in which to identify new yeast gene functions. The chapters are written in a readable style with useful background information, technical tips and specific experimental protocols included as appropriate, enabling both the novice and the experienced yeast researcher to adopt new procedures with confidence.
Download
Advanced Bacterial Genetics: Use of Transposons and Phage for Genomic Engineering
Advanced Bacterial Genetics: Use of Transposons and Phage for Genomic Engineering, Volume 421 (Methods in Enzymology)
by Kelly T Hughes (Editor)
Product Details:
* Hardcover: 320 pages
* Publisher: Academic Press; 1 edition (February 27, 2007)
* Language: English
* ISBN-10: 0123737494
Book Description
The critically acclaimed laboratory standard for more than fifty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant todaytruly an essential publication for researchers in all fields of life sciences. This new volume presents methods related to the use of bacterial genetics for genomic engineering. The book includes sections on strain collections and genetic nomenclature; transposons; and phage.
Download
by Kelly T Hughes (Editor)
Product Details:
* Hardcover: 320 pages
* Publisher: Academic Press; 1 edition (February 27, 2007)
* Language: English
* ISBN-10: 0123737494
Book Description
The critically acclaimed laboratory standard for more than fifty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with over 400 volumes (all of them still in print), the series contains much material still relevant todaytruly an essential publication for researchers in all fields of life sciences. This new volume presents methods related to the use of bacterial genetics for genomic engineering. The book includes sections on strain collections and genetic nomenclature; transposons; and phage.
Download
Restriction Endonucleases
Restriction Endonucleases (Nucleic Acids and Molecular Biology)
by Alfred M. Pingoud (Editor)
Product Details:
* Hardcover: 443 pages
* Publisher: Springer; 1 edition (December 16, 2004)
* Language: English
* ISBN-10: 3540205020
Book Description:
Restriction enzymes are highly specific nucleases which occur ubiquitously among prokaryotic organisms, where they serve to protect bacterial cells against foreign DNA. Many different types of restriction enzymes are known, among them multi-subunit enzymes which depend on ATP or GTP hydrolysis for target site location. The best known representatives, the orthodox type II restriction endonucleases, are homodimers which recognize palindromic sequences, 4 to 8 base pairs in length, and cleave the DNA within or immediately adjacent to the recognition site. In addition to their important biological role (up to 10 % of the genomes of prokaryotic organisms code for restriction/modification systems!), they are among the most important enzymes used for the analysis and recombination of DNA. In addition, they are model systems for the study of protein-nucleic acids interactions and, because of their ubiquitous occurence, also for the understanding of the mechanisms of evolution.
Download
Mirror
by Alfred M. Pingoud (Editor)
Product Details:
* Hardcover: 443 pages
* Publisher: Springer; 1 edition (December 16, 2004)
* Language: English
* ISBN-10: 3540205020
Book Description:
Restriction enzymes are highly specific nucleases which occur ubiquitously among prokaryotic organisms, where they serve to protect bacterial cells against foreign DNA. Many different types of restriction enzymes are known, among them multi-subunit enzymes which depend on ATP or GTP hydrolysis for target site location. The best known representatives, the orthodox type II restriction endonucleases, are homodimers which recognize palindromic sequences, 4 to 8 base pairs in length, and cleave the DNA within or immediately adjacent to the recognition site. In addition to their important biological role (up to 10 % of the genomes of prokaryotic organisms code for restriction/modification systems!), they are among the most important enzymes used for the analysis and recombination of DNA. In addition, they are model systems for the study of protein-nucleic acids interactions and, because of their ubiquitous occurence, also for the understanding of the mechanisms of evolution.
Download
Mirror
Imaging Cellular and Molecular Biological Functions
Imaging Cellular and Molecular Biological Functions (Principles and Practice)
by Spencer L. Shorte (Editor), Friedrich Frischknecht (Editor)
Product Details:
* Hardcover: 435 pages
* Publisher: Springer; 1 edition (October 2007)
* Language: English
* ISBN-10: 3540713301
Book Description
“Imaging Cellular and Molecular Biological Function” provides a unique selection of essays by leading experts, aiming at scientist and student alike who are interested in all aspects of modern imaging, from its application and up-scaling to its development. The chapter content ranges from the basic through to complex overview of method and protocols, and there is also practical and detailed “how-to” content on important, but rarely addressed topics. This first edition features all-colour-plate chapters and a unique continuously updated website forum where contributors and readers share software utilities described herein including a limited license version of the imaging platform management software “PPMS” version 1.0 release, plus relevant new publications and links to other important resources.
Download
Password:gigapedia.org
by Spencer L. Shorte (Editor), Friedrich Frischknecht (Editor)
Product Details:
* Hardcover: 435 pages
* Publisher: Springer; 1 edition (October 2007)
* Language: English
* ISBN-10: 3540713301
Book Description
“Imaging Cellular and Molecular Biological Function” provides a unique selection of essays by leading experts, aiming at scientist and student alike who are interested in all aspects of modern imaging, from its application and up-scaling to its development. The chapter content ranges from the basic through to complex overview of method and protocols, and there is also practical and detailed “how-to” content on important, but rarely addressed topics. This first edition features all-colour-plate chapters and a unique continuously updated website forum where contributors and readers share software utilities described herein including a limited license version of the imaging platform management software “PPMS” version 1.0 release, plus relevant new publications and links to other important resources.
Download
Password:gigapedia.org
Posted in: ebooks